Melanosis Coli - An Atypical Presentation

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Melanosis coli.

n engl j med 368;24 nejm.org june 13, 2013 2303 A 50-year-old woman underwent colonoscopy for rectal bleeding. Her entire colon appeared dark brown and black, a finding consistent with the diagnosis of melanosis coli (Panel A). Random biopsy specimens from the descending colon revealed sheets and clusters of macrophages laden with brownish pigment in the lamina propria (Panel B, arrow). A tiny,...

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Melanosis coli

Melanosis coli denotes brownish discoloration of the colonic mucosa found on endoscopy or histopathologic examination. The condition has no specific symptom on its own. It is a fairly frequent incidental finding of colonic biopsies and resection specimens. The pigmentation is caused by apoptotic cells which are ingested by macrophages and subsequently transported into the lamina propria, where ...

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ژورنال

عنوان ژورنال: Journal of Medicine

سال: 1970

ISSN: 2075-5384,1997-9797

DOI: 10.3329/jom.v11i2.5469